In this article:
Protocol development in integrative medicine is not typically a simple process. Individuals require individualized care, and what works for one patient may not work for another.
As a result, the Fullscript Integrative Medical Advisory team advises using an evidence-informed approach to protocol development. To simplify this process for practitioners, we have assembled a sampling of evidence-based standardized protocols that practitioners can use as a foundation when developing individualized protocols.
To establish these protocols, we first developed a Rating Scale that could be used to discern the rigor of evidence supporting a specific nutrient’s therapeutic effect.
The following protocols were developed using only A through C-quality evidence. These are categorized as follows:
A Systematic review or meta-analysis
B Randomized Double Blind Placebo Controlled (RDBPC) 2+ studies and/or 1 study with 50 + subjects
C Randomized Double Blind Placebo Controlled (RDBPC) 1 study
Please refer to the complete Rating Scale for further information.
The ingredients included in these protocols are based on a review of existing clinical research, with a priority placed on systematic reviews and meta-analyses, classified as A in the Rating Scale.
These protocols are intended to form a foundation for developing individualized treatment plans. Clinician discretion is highly advised, as ingredients can vary in safety and effectiveness, depending on the needs of the individual patient.
Ingredient-Based Protocol: Hypertension
300-450mg of elemental magnesium, total per day,1 to 6 months1,2
- Consistent supplementation resulted in a decrease of both systolic and diastolic blood pressure1,2
- An inverse correlation between levels of circulating magnesium and the incidence of hypertension has been clearly identified3,4
Search for Magnesium in the Fullscript catalog.
2.4g, total per day, minimum 6 months5
- Reduction in blood pressure observed in patients with mild to moderate hypertension5
- Compared to placebo, L-arginine supplementation was shown to lower systolic blood pressure in patients with gestational hypertension6
Search for L-arginine in the Fullscript catalog.
Garlic (Allium Sativum)
300 to 960mg, total per day, minimum 8 to 12 weeks7,8,9
- Consistent supplementation for 8-12 weeks has demonstrated reduction in both systolic and diastolic blood pressure7,8,9,10,11
- Garlic supplementation is widely considered a safe and effective approach to hypertension7,8,10,11
Search for Garlic in the Fullscript catalog.
Adding Protocols to your Fullscript Catalog
Create a Template
- Click the “Prescriptions” button
- Click “Manage your prescription templates”
- Click “Create a new template”
- Add a title, products, dosing, message, and attachments
- Click “Save Template”
Templates can be accessed and applied when creating a new prescription for your patients.
Write a Prescription
- Click the “New Prescription” button
- Click the “Templates” button in the right-hand menu column
- Click the “Apply” button beside the template you wish to apply
- Modify as needed
- Click the “Send to Patient” button!
Create a Category
- Click the Catalog button
- Click the “Your Favorites” tab
- Click “Add Category” and add name
- Add products
Categories can be used for quick reference or for patient use when accessing the catalog (depending on catalog settings).
Visit the Fullscript Integrative Clinical Education Hub for a full review of the literature used to develop this protocol.
We’d be happy to help you create a protocol containing these ingredients in your Fullscript catalog! Contact our Customer Success team for assistance.
1 (A) - https://www.ncbi.nlm.nih.gov/pubmed/28724644
2 (A) - https://www.ncbi.nlm.nih.gov/pubmed/27402922
3 (A) - https://www.ncbi.nlm.nih.gov/pubmed/28476161
4 (A) - https://www.ncbi.nlm.nih.gov/pubmed/28927411
5 (B) - https://www.ncbi.nlm.nih.gov/pubmed/27817128
6 (A) - https://www.ncbi.nlm.nih.gov/pubmed/23435582
7 (B) - https://www.ncbi.nlm.nih.gov/pubmed/23404465?dopt=Abstract
8 (B) - https://www.ncbi.nlm.nih.gov/pubmed/20594781?dopt=Abstract
9 (B) - https://www.ncbi.nlm.nih.gov/pubmed/19390538?dopt=Abstract
10 (A) - https://www.ncbi.nlm.nih.gov/pubmed/26764326
11 (A) - https://www.ncbi.nlm.nih.gov/pubmed/25837272